Marie Piraud

Nov 27, 2024 | nature.com | Lin Yang |Daniel Razansky |Marie Piraud |Fabian Isensee |Wolfgang G. Kreyling

AbstractTargeted (nano-)drug delivery is essential for treating respiratory diseases, which are often confined to distinct lung regions. However, spatio-temporal profiling of drugs or nanoparticles (NPs) and their interactions with lung macrophages remains unresolved.

Apr 22, 2024 | nature.com | Mihail Ivilinov Todorov |Benedikt Wiestler |Marie Piraud |Daniel Rueckert |Maria Rohm |Stephan Herzig | +1 more

AbstractAutomated detection of specific cells in three-dimensional datasets such as whole-brain light-sheet image stacks is challenging. Here, we present DELiVR, a virtual reality-trained deep-learning pipeline for detecting c-Fos+ cells as markers for neuronal activity in cleared mouse brains. Virtual reality annotation substantially accelerated training data generation, enabling DELiVR to outperform state-of-the-art cell-segmenting approaches.

Apr 21, 2024 | flipboard.com | Doris Kaltenecker |Rami Al-Maskari |Moritz Negwer |Luciano Hoeher |Florian Kofler |Mihail I. Todorov | +12 more

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