Marija Milisavljevic

Sep 14, 2024 | analyticalsciencejournals.onlinelibrary.wiley.com | Marija Milisavljevic |Teresa Rodriguez |Teresa Rodríguez

1 INTRODUCTION Synthetic DNA is not only essential for biological research but also compelling as a durable, high-density storage medium for information storage applications (Church et al., 2012; Erlich & Zielinski, 2017; Goldman et al., 2013).

Jun 11, 2024 | biorxiv.org | Courtney Carlson |Theresa B Loveless |Patrick Kelly |Marija Milisavljevic

AbstractTerminal deoxynucleotidyl transferase (TdT) is a unique DNA polymerase capable of template-independent extension of DNA with random nucleotides. TdT's de novo DNA synthesis ability has found utility in DNA recording, DNA data storage, oligonucleotide synthesis, and nucleic acid labeling, but TdT's intrinsic nucleotide biases limit its versatility in such applications.