Marina K Smiley

Jul 20, 2024 | biorxiv.org | Beatrice Bottura |Gail McConnell |Lindsey C Florek |Marina K Smiley

AbstractChemical gradients and the emergence of distinct microenvironments in biofilms are vital to the stratification, maturation and overall function of microbial communities. These gradients have been well characterised throughout the biofilm mass but the microenvironment of recently discovered nutrient transporting channels in Escherichia coli biofilms remains unexplored.

Aug 24, 2023 | biorxiv.org | Alicia G Mendoza |Danielle Guercio |Marina K Smiley |GAURAV SHARMA

AbstractMany bacterial histidine kinases work in two-component systems that combine into larger multi-kinase networks. NahK is one of the kinases in the GacS Multi-Kinase Network (MKN), which is the MKN that controls biofilm regulation in the opportunistic pathogen Pseudomonas aeruginosa (P. aeruginosa). This network has also been associated with regulating many virulence factors P. aeruginosa secretes to cause disease. However, the individual role of each kinase is unknown.

Jun 1, 2023 | biorxiv.org | Marina K Smiley |Alexa Price-Whelan |Lars E.P. Dietrich |Doran C Sekaran

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Feb 16, 2023 | biorxiv.org | Christopher Evans |Mian Wei |Marina K Smiley |Sean Asahara Thio

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