Mario M. Modena

Feb 13, 2023 | onlinelibrary.wiley.com | Wei Wei |Andreas Hierlemann |Fernando Cardes |Mario M. Modena

2.4 The BBB Platform as an Effective In Vitro Model for Recapitulating Ischemic Injuries After confirming that our system was capable of monitoring rapid variations in BBB permeability and EC-layer organization, we challenged our barrier model with an ischemia-like insult by exposing the model to oxygen glucose deprivation (OGD), which is a commonly applied method to induce ischemic injuries in vitro[64] (Figure 5a).