Marion Mateos

Jun 6, 2024 | nature.com | Dong-Anh Khuong-Quang |Chelsea Mayoh |Marie Wong |Sumanth Nagabushan |Veronica Yeung |Natacha Omer | +15 more

AbstractRecent research showed that precision medicine can identify new treatment strategies for patients with childhood cancers. However, it is unclear which patients will benefit most from precision-guided treatment (PGT).

Jun 6, 2024 | nature.com | Dong-Anh Khuong-Quang |Chelsea Mayoh |Marie Wong |Sumanth Nagabushan |Veronica Yeung |Natacha Omer | +15 more

AbstractRecent research showed that precision medicine can identify new treatment strategies for patients with childhood cancers. However, it is unclear which patients will benefit most from precision-guided treatment (PGT).

May 12, 2024 | mja.com.au | Timothy EG |Santosh Valvi |Neevika Manoharan |Marion Mateos

Diffuse intrinsic pontine glioma (DIPG) is a high grade glioma of the pons, predominantly occurring in children.

Sep 26, 2023 | nature.com | Peter Downie |Elizabeth McKinnon |Michael Osborn |Tim Prestidge |Siobhan Cross |Caroline Bateman | +3 more

TO THE EDITOR: Acute lymphoblastic leukaemia (ALL) in infancy, defined as ≤1 year of age at diagnosis, is rare with an incidence of 1.8 cases per 100,000 [1]. KMT2A-gene rearrangements are present in up to 80% of infants with ALL and are associated with a poor prognosis.

Sep 19, 2023 | nature.com | Claire E. Wakefield |Kate Hetherington |Eden G. Robertson |Mark Donoghoe |Jacqueline Hunter |Janine Vetsch | +6 more

AbstractPaediatric precision oncology aims to match therapeutic agents to driver gene targets. We investigated whether parents and patients regret participation in precision medicine trials, particularly when their hopes are unfulfilled. Parents and adolescent patients completed questionnaires at trial enrolment (T0) and after receiving results (T1). Parents opted-in to an interview at T1. Bereaved parents completed a questionnaire 6-months post-bereavement (T1B).