Mark Haid

Oct 2, 2024 | nature.com | Bo Burla |Makoto Arita |Takeshi Bamba |Britta Brügger |Benoit Colsch |Alex Dickens | +29 more

AbstractIn this community effort, we compare measurements between 34 laboratories from 19 countries, utilizing mixtures of labelled authentic synthetic standards, to quantify by mass spectrometry four clinically used ceramide species in the NIST (National Institute of Standards and Technology) human blood plasma Standard Reference Material (SRM) 1950, as well as a set of candidate plasma reference materials (RM 8231).

Aug 21, 2023 | nature.com | Andrew Brown |Mun-Gwan Hong |Robert Caiazzo |Giuseppe Giordano |Mark Haid |Torben Frøstrup Hansen | +17 more

AbstractWe evaluate the shared genetic regulation of mRNA molecules, proteins and metabolites derived from whole blood from 3029 human donors. We find abundant allelic heterogeneity, where multiple variants regulate a particular molecular phenotype, and pleiotropy, where a single variant associates with multiple molecular phenotypes over multiple genomic regions.