Marta Vittani

1 month ago | biorxiv.org | Marta Vittani |Ashley Lee |Xiaowen Wang |Yuichi Hiraoka

AbstractSustained labeling of fluids is crucial for their investigation in animal models. Here, we introduce a mouse line (Alb-mSc-ST), where blood and interstitial fluid are labeled with the red fluorescent protein mScarlet and SpyTag. The SpyTag-SpyCatcher technology is exploited to monitor circulating fluid properties by biosensors or detect blood-brain barrier disruption.