Martin Mclaughlin

Dec 11, 2024 | nature.com | Djenet Bousbaine |Pranav Lalgudi |David Li |Sunit Jain |Martin Mclaughlin |Inta Gribonika | +4 more

AbstractThe ubiquitous skin colonist Staphylococcus epidermidis elicits a CD8+ T cell response pre-emptively, in the absence of an infection1. However, the scope and purpose of this anti-commensal immune program are not well defined, limiting our ability to harness it therapeutically. Here, we show that this colonist also induces a potent, durable, and specific antibody response that is conserved in humans and non-human primates. A series of S.