Martine Cohen-Solal

Nov 2, 2023 | nature.com | Maria Nethander |Sofia Movérare-Skrtic |Anders Kämpe |Ene Reimann |Louise Grahnemo |Martine Cohen-Solal | +10 more

AbstractOsteoporotic fracture is among the most common and costly of diseases. While reasonably heritable, its genetic determinants have remained elusive. Forearm fractures are the most common clinically recognized osteoporotic fractures with a relatively high heritability. To establish an atlas of the genetic determinants of forearm fractures, we performed genome-wide association analyses including 100,026 forearm fracture cases. We identified 43 loci, including 26 new fracture loci.