Louise Grahnemo

Nov 20, 2024 | healio.com | Michael Monostra |Richard Smith |Louise Grahnemo

You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Key takeaways:Men with lower levels of SHBG in the UK Biobank were less likely to sustain any fracture during follow-up. Lower testosterone levels were associated with an increased fracture risk after adjusting for SHBG.

Aug 13, 2024 | nature.com | Louise Grahnemo |Pekka Jousilahti |Veikko Salomaa |Aki S Havulinna

AbstractThe gut microbiota (GM) can regulate bone mass, but its association with incident fractures is unknown. We used Cox regression models to determine whether the GM composition is associated with incident fractures in the large FINRISK 2002 cohort (n = 7043, 1092 incident fracture cases, median follow-up time 18 years) with information on GM composition and functionality from shotgun metagenome sequencing.

May 22, 2024 | nature.com | Louise Grahnemo

AbstractOptic disc drusen (ODD) are calcified, acellular bodies, seen in the optic nerve head of up to 2% of the population. Although seldomly affecting visual acuity, visual field defects are common, and severe, ischemic complications causing irreversible vision loss are known to occur. Different treatment strategies for ODD have been explored, but so far without success.

Nov 2, 2023 | nature.com | Maria Nethander |Sofia Movérare-Skrtic |Anders Kämpe |Ene Reimann |Louise Grahnemo |Martine Cohen-Solal | +10 more

AbstractOsteoporotic fracture is among the most common and costly of diseases. While reasonably heritable, its genetic determinants have remained elusive. Forearm fractures are the most common clinically recognized osteoporotic fractures with a relatively high heritability. To establish an atlas of the genetic determinants of forearm fractures, we performed genome-wide association analyses including 100,026 forearm fracture cases. We identified 43 loci, including 26 new fracture loci.

Apr 20, 2023 | newsbreak.com | Louise Grahnemo

Florida's Best Barbecue Restaurant is Also the State's Best Locally-Owned Restaurant, According to Southern Living