Maryam M. Shanechi

Sep 6, 2024 | nature.com | Omid G Sani |Bijan Pesaran |Maryam M. Shanechi

AbstractUnderstanding the dynamical transformation of neural activity to behavior requires new capabilities to nonlinearly model, dissociate and prioritize behaviorally relevant neural dynamics and test hypotheses about the origin of nonlinearity. We present dissociative prioritized analysis of dynamics (DPAD), a nonlinear dynamical modeling approach that enables these capabilities with a multisection neural network architecture and training approach.

Jun 2, 2024 | nature.com | Lucine L. Oganesian |Maryam M. Shanechi

AbstractNeuropsychiatric disorders such as major depression are a leading cause of disability worldwide with standard treatments, including psychotherapy or medication, failing many patients.

Feb 9, 2024 | pnas.org | Parsa Vahidi |Omid G Sani |Maryam M. Shanechi |Samo Curk

Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma Lourdes Sainero-Alcolado https://orcid.org/0000-0002-9406-6478, Elisa Garde-Lapido https://orcid.org/0009-0001-5321-1253, Marteinn Thor Snaebjörnsson, +7 , Sarah Schoch, Irene Stevens https://orcid.org/0000-0003-3823-1499, María Victoria Ruiz-Pérez, Christine Dyrager https://orcid.org/0000-0003-4647-9769, Vicent Pelechano, Håkan Axelson https://orcid.org/0000-0002-7749-5043, Almut...

Feb 8, 2024 | pnas.org | Parsa Vahidi |Omid G Sani |Maryam M. Shanechi |Samo Curk

Given the way that Mark S. George describes the early days of his experiments with transcranial magnetic stimulation (TMS), potential patients might be wary. A professor of psychiatry at the Medical University of South Carolina and a pioneer of TMS, George recounts, for example, how the electrical circuits delivering current to coils would explode “with a blue flame” not all that far from the subject and the scientist.

Feb 6, 2024 | pnas.org | Parsa Vahidi |Omid G Sani |Maryam M. Shanechi |Samo Curk

The shape of Nature’s stingers revealedEdited by William Nix, Stanford University, Stanford, CA; received September 19, 2023; accepted December 6, 2023SignificanceAs ubiquitous defense mechanisms in Nature, stinger-like structures cover a size range over six orders of magnitude. While their composition varies, we uncovered a common geometric trait: a non-linear relationship between diameter and distance from the tip, following a power law with an exponent universally between 2 and 3.