Masanobu Komatsu

Featured in: Favicon

Articles

Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1

Feb 24, 2024 | cell.com | Byzova T.V |Jose Herrera |José Herrera |Masanobu Komatsu

Highlights•Quiescent endothelial cells guide quiescence of neighboring cells via cell contact•This contact inhibition is mediated by Akt3 and applied by Jagged1•Cell contact provides feedback reinforcement of the barrier in the neighborhood•R-Ras-Akt3-Jagged1-mediated intercellular crosstalk provides angiostasisSummaryCommunication between adjacent endothelial cells is important for the homeostasis of blood vessels.

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.