Massimo Cristofanilli

Oct 25, 2024 | onclive.com | Massimo Cristofanilli

CommentaryVideoOctober 25, 2024Author(s):Fact checked by:,Massimo Cristofanilli, MD, discusses the use of circulating tumor DNA for minimal residual disease detection in patients with breast cancer.

Oct 1, 2024 | nature.com | Ashton C. Berger |Massimo Cristofanilli |Jason A Burdick |Virginia F. Borges

AbstractCollagen plays a critical role in regulating breast cancer progression and therapeutic resistance. An improved understanding of both the features and drivers of tumor-permissive and -restrictive collagen matrices are critical to improve prognostication and develop more effective therapeutic strategies. In this study, using a combination of in vitro, in vivo and bioinformatic experiments, we show that type III collagen (Col3) plays a tumor-restrictive role in human breast cancer.

Feb 13, 2023 | onclive.com | Massimo Cristofanilli |Sara M. Tolaney

Transcript:Massimo Cristofanilli, MD: I think hormone receptor-positive patients in early oligometastatic breast cancer are the majority of patients who come to the clinic or a community oncologist who treats breast cancer. There are many different studies indicating the importance of risk stratification, molecular assessment, targeted therapy, and different endocrine agents.

Feb 6, 2023 | onclive.com | Massimo Cristofanilli |Sara M. Tolaney

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Feb 6, 2023 | onclive.com | Massimo Cristofanilli |Sara M. Tolaney

Transcript:Massimo Cristofanilli, MD: One more thing about this case. This patient, being stage IV, had breast surgery up front. What’s the role of breast surgery in metastatic disease, especially in ER [estrogen receptor] positive? Sara Tolaney, MD, MPH: That’s an excellent question. Generally speaking, I haven’t been taking patients with de novo metastatic disease to surgery.