Matthew T Weirauch

Oct 29, 2024 | nature.com | Matthew T Weirauch

AbstractMultinucleated skeletal muscle cells need to acquire additional nuclei through fusion with activated skeletal muscle stem cells when responding to both developmental and adaptive growth stimuli. A fundamental question in skeletal muscle biology has been the reason underlying this need for new nuclei in cells that already harbor hundreds of nuclei.

Jan 26, 2024 | scienceblog.cincinnatichildrens.org | Leah C. Kottyan |Matthew T Weirauch |Marc E. Rothenberg

Symptoms of eosinophilic esophagitis (EoE) mirror those of many common conditions, making it challenging to diagnose. Surgical biopsy is the diagnostic gold standard, but no guidelines exist to help clinicians decide whether to perform one. Researchers at Cincinnati Children’s hope to improve the way genetic risk can be incorporated into decision making with help from a novel, DNA-based tool called massively parallel reporter assays (MPRA).