Leah C. Kottyan

Jun 17, 2024 | nature.com | Leah C. Kottyan

AbstractType 2 diabetes (T2D) is caused by both genetic and environmental factors and is associated with an increased risk of cardiorenal complications and mortality. Though disproportionately affected by the condition, African Americans (AA) are largely underrepresented in genetic studies of T2D, and few estimates of heritability have been calculated in this race group.

Jan 26, 2024 | scienceblog.cincinnatichildrens.org | Leah C. Kottyan |Matthew T Weirauch |Marc E. Rothenberg

Symptoms of eosinophilic esophagitis (EoE) mirror those of many common conditions, making it challenging to diagnose. Surgical biopsy is the diagnostic gold standard, but no guidelines exist to help clinicians decide whether to perform one. Researchers at Cincinnati Children’s hope to improve the way genetic risk can be incorporated into decision making with help from a novel, DNA-based tool called massively parallel reporter assays (MPRA).

Feb 6, 2023 | nature.com | Lili Liu |Atlas Khan |Elena Sanchez-Rodriguez |Junying Zhang |Halima Moncrieffe |Leah C. Kottyan | +14 more

Correction to: Nature Communications https://doi.org/10.1038/s41467-022-34456-6, published online 11 November 2022The original version of this Article contained two errors in table 1. The correct version of the 13th row of the first column states “Chinese (East Asian)” instead of the incorrect “Chinese (European)”. The correct version of the 14th row of the first column states “Japanese (East Asian)” instead of the incorrect “Japanese (European)”.