Megan Nguyen

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Targeting DBS to the centrolateral thalamic nucleus improves movement in a lesion-based model of acquired cerebellar dystonia in mice

May 21, 2024 | biorxiv.org | Megan Nguyen |Amanda Brown |Tao Lin |Roy V. Sillitoe

AbstractDystonia is the third most common movement disorder and an incapacitating co-morbidity in a variety of neurologic conditions. Dystonia can be caused by genetic, degenerative, idiopathic, and acquired etiologies, which are hypothesized to converge on a dystonia network consisting of the basal ganglia, thalamus, cerebellum, and cerebral cortex.

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