Mehdi Farokhnia

Jul 10, 2024 | onlinelibrary.wiley.com | Ramin Mojtabai |Ryoko Susukida |Mehdi Farokhnia |Clinical Psychoneuroendocrinology

• , . Serotonin-altering medications and desire, consumption and effects of alcohol-treatment implications . EXS. ; : – . • , , , , . A randomized, double-blind, placebo-controlled trial of ondansetron for the treatment of cocaine use disorder with post hoc pharmacogenetic analysis . Drug Alcohol Depend. ; :109074. • , , , , , , et al. Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving . Sci Adv. ; :eaay0351. • , , .

Jun 5, 2024 | psychiatrictimes.com | Mehdi Farokhnia

In this Mental Health Minute, Mehdi Farokhnia, MD, MPH, of theNational Institutes of Health (NIH) Intramural Research Program, the National Institute on Drug Abuse (NIDA), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) shares highlights from “Glucagon-like peptide-1 (GLP-1) receptor agonism as a potential pharmacotherapy for alcohol use disorder: converging evidence from rodent and early human studies,” a presentation he delivered as part of the Pharmaceutical Pipeline...

Nov 24, 2023 | nature.com | Lorenzo Leggio |Christian S Hendershot |Mehdi Farokhnia |Anders Fink-Jensen |Mette Kruse Klausen

Preclinical and initial human studies suggest that glucagon-like peptide-1 receptor agonists may be promising treatments for alcohol use disorder, but existing approved treatments should be used until safety and efficacy is demonstrated in clinical trials.

Nov 22, 2023 | mentalhealth.bmj.com | Madeline Crozier |Mehdi Farokhnia |Susan Persky |Lorenzo Leggio

DiscussionThis study aimed to investigate the relationship between self-stigma and various alcohol-related outcomes within a clinical context. Specifically, we examined the association between alcohol-related self-stigma, as assessed by the SSAD, and the severity of alcohol use, levels of alcohol consumption, alcohol obsession and compulsion, and alcohol craving.

May 16, 2023 | insight.jci.org | JCI Insight |Vicky Chuong |Mehdi Farokhnia |Sophia Khom

ResearchIn-Press PreviewEndocrinologyNeuroscienceOpen Access | 10.1172/jci.insight.170671 JCI Insight. https://doi.org/10.1172/jci.insight.170671. Copyright © 2023, Chuong et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.