Mehran Karimzadeh

Nov 21, 2024 | nature.com | Mehran Karimzadeh |Helen Li |Olivier Elemento |James Zou |Fereydoun Hormozdiari |Babak Alipanahi

AbstractLiquid biopsies have the potential to revolutionize cancer care through non-invasive early detection of tumors. Developing a robust liquid biopsy test requires collecting high-dimensional data from a large number of blood samples across heterogeneous groups of patients. We propose that the generative capability of variational auto-encoders enables learning a robust and generalizable signature of blood-based biomarkers.

May 19, 2023 | physiciansweekly.com | Rebecca Shover |Mehran Karimzadeh

Orphan non-coding RNAs demonstrated efficacy for accurate, sensitive, and early detection of NSCLC. “Orphan non-coding RNAs (oncRNAs) are a novel category of small non-coding RNAs that are present in the tumor tissue and blood of people with cancer and largely absent in people without cancer,” Mehran Karimzadeh, PhD, and colleagues wrote.