Meisam Hoseinyazdi

Mar 12, 2024 | jnis.bmj.com | Vivek S. Yedavalli |Manisha Koneru |Meisam Hoseinyazdi |Cynthia Greene

AbstractBackground Poor venous outflow (VO) profiles are associated with unfavorable outcomes in patients with acute ischemic stroke caused by large vessel occlusion (AIS-LVO), despite achieving successful reperfusion. The objective of this study is to assess the association between mortality and prolonged venous transit (PVT), a novel visual qualitative VO marker on CT perfusion (CTP) time to maximum (Tmax) maps.

Dec 25, 2023 | onlinelibrary.wiley.com | Manisha Koneru |Meisam Hoseinyazdi |Dhairya A. Lakhani |Cynthia Greene

Background and Purpose In large vessel occlusion (LVO) stroke patients, relative cerebral blood flow (rCBF)<30% volume thresholds are commonly used in treatment decisions. In the early time window, nearly infarcted but salvageable tissue volumes may lead to pretreatment overestimates of infarct volume, and thus potentially exclude patients who may otherwise benefit from intervention.

Dec 6, 2023 | onlinelibrary.wiley.com | Dhairya A. Lakhani |Aneri Balar |Manisha Koneru |Meisam Hoseinyazdi

Background and Purpose Acute ischemic stroke due to large vessel occlusion (AIS-LVO) is a major cause of functional dependence. Collateral status (CS) is an important determinant of functional outcomes. Pretreatment CT perfusion (CTP) parameters serve as reliable surrogates of CS. Penumbra Salvage Index (PSI) is another parameter predictive of functional outcomes in AIS-LVO. The aim of this study is to assess the relationship of pretreatment CTP parameters with PSI.

Nov 6, 2023 | onlinelibrary.wiley.com | Richard J. Wang |Jing Huang |Alireza Mohseni |Meisam Hoseinyazdi

Introduction Acute ischemic stroke (AIS) is a key cause of mortality and morbidity worldwide.1 Up to 30% of AIS cases are caused by anterior circulation large vessel occlusions (LVOs), which have been shown to cause disproportionately worse outcomes than other sites of occlusion.2, 3 For these patients, mechanical thrombectomy (MT) has become the standard of care for up to 24 hours in patients deemed eligible.4, 5 The extent of reperfusion achieved after MT is typically assessed with the...