Dhairya A. Lakhani

Apr 19, 2024 | mdpi.com | Dhairya A. Lakhani |Aneri Balar |Hamza Salim |Manisha Koneru

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Mar 10, 2024 | mdpi.com | Dhairya A. Lakhani |Aneri Balar |Manisha Koneru |Sijin Wen

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.

Jan 7, 2024 | nature.com | Dhairya A. Lakhani |Vishal Patel |Chen Lin |Sina Straub |Zbigniew K. Wszolek |Philip W. Tipton

AbstractParkinson’s disease (PD) is a prevalent neurodegenerative disorder that presents a diagnostic challenge due to symptom overlap with other disorders. Neuromelanin (NM) imaging is a promising biomarker for PD, but adoption has been limited, in part due to subpar performance at standard MRI field strengths.

Dec 25, 2023 | onlinelibrary.wiley.com | Manisha Koneru |Meisam Hoseinyazdi |Dhairya A. Lakhani |Cynthia Greene

Background and Purpose In large vessel occlusion (LVO) stroke patients, relative cerebral blood flow (rCBF)<30% volume thresholds are commonly used in treatment decisions. In the early time window, nearly infarcted but salvageable tissue volumes may lead to pretreatment overestimates of infarct volume, and thus potentially exclude patients who may otherwise benefit from intervention.

Dec 6, 2023 | onlinelibrary.wiley.com | Dhairya A. Lakhani |Aneri Balar |Manisha Koneru |Meisam Hoseinyazdi

Background and Purpose Acute ischemic stroke due to large vessel occlusion (AIS-LVO) is a major cause of functional dependence. Collateral status (CS) is an important determinant of functional outcomes. Pretreatment CT perfusion (CTP) parameters serve as reliable surrogates of CS. Penumbra Salvage Index (PSI) is another parameter predictive of functional outcomes in AIS-LVO. The aim of this study is to assess the relationship of pretreatment CTP parameters with PSI.