Melody Wu

Jun 1, 2024 | nature.com | Qingtao Sun |Miriam Ferrer |Melody Wu |Youngkyu Park |Jessica Tollkuhn |Tobias Janowitz

AbstractInterleukin-6 (IL-6) has been long considered a key player in cancer cachexia. It is believed that sustained elevation of IL-6 production during cancer progression causes brain dysfunctions, which ultimately result in cachexia. However, how peripheral IL-6 influences the brain remains poorly understood. Here we show that neurons in the area postrema (AP), a circumventricular structure in the hindbrain, is a critical mediator of IL-6 function in cancer cachexia in male mice.

May 13, 2023 | biorxiv.org | Jessica Tollkuhn |Katherine Denney |Melody Wu |Soyoun Moon

New Results doi: https://doi.org/10.1101/2023.05.12.540606 AbstractThe socially monogamous prairie vole (Microtus ochrogaster) and promiscuous meadow vole (Microtus pennsylvanicus) are closely related, but only prairie voles display long-lasting pair bonds, biparental care, and selective aggression towards unfamiliar individuals after pair bonding.