Michael Fishman

Sep 23, 2024 | chemistry-europe.onlinelibrary.wiley.com | Tomasz Kochańczyk |Michael Fishman |Christopher D. Lima

Conjugation of ubiquitin (Ub) and structurally related ubiquitin-like proteins (Ubl's), essential for many cellular processes, employs muti-step reactions orchestrated by specific E1, E2 and E3 enzymes. The E1 enzyme activates the Ub/Ubl C-terminus in an ATP-dependent process that results in the formation of a thioester linkage with the E1 active site cysteine.

Sep 11, 2024 | onlinelibrary.wiley.com | Michael Fishman |Kasra Amirdelfan |Jeffery Peacock |David Provenzano

INTRODUCTION Chronic pain impacts an estimated 20% of adults globally.1 Chronic back pain and leg pain are recognized to place significant burdens on both patient quality of life (QoL) and healthcare system resources.2, 3 Spinal cord stimulation (SCS) is a highly effective and established minimally invasive and non-pharmacologic treatment indicated as an aid in the management of chronic, intractable pain of the trunk and/or limbs.

May 7, 2024 | kellogg.northwestern.edu | Michael Fishman |Jonathan Parker |Ludwig Straub

Home | Faculty & Research Overview | Research We analyze a dynamic credit market where banks choose lending standards,modeled as costly effort to screen out bad borrowers. Tighter standards worsenthe borrower pool, increasing banks’ incentives to employ tight standards in thefuture. This dynamic complementarity in lending standards can amplify andprolong downturns, decreasing lending and increasing credit spreads.

Mar 6, 2024 | epicdope.com | Rajarsi Chakraborty |Laurie Metcalf |Lecy Goranson |Michael Fishman

SummaryJackie’s liberal mindset and stance on drag queens revives her conflict with Roseanne in the ABC revival of the show. The Connors season 6 episode 4 starts a conflict when some songs are banned by the music teacher because of their drag queen references. Several years after the canceled revival, ‘The Conners’ finally resurrects Jackie and Roseanne’s original conflict. Although the family comedy mainly featured Roseanne and the Dan Conners family, Jackie also got a lot of focus.

Dec 14, 2023 | mdpi.com | Michael Fishman |Ahish Chitneni |Alaa Abd-Elsayed |Samuel Grodofsky

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