Michael Hsiao

1 month ago | nature.com | Wei-Jiunn Lee |Michael Hsiao |Shun-Fa Yang |Yi-Chieh Yang

AbstractThe intricate involvement of the histaminergic system, encompassing histamine and histamine receptors, in the progression of diverse neoplasias has attracted considerable scrutiny. Histamine receptor H1 (HRH1) was reported to be overexpressed in several cancer types, but its specific functional implications in oral squamous cell carcinoma (OSCC) predominantly remain unexplored.

Jan 14, 2025 | mdpi.com | Yuan-Chieh Yeh |Bashir Lawal |Michael Hsiao |Tse-Hung Huang

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May 1, 2024 | nature.com | Michael Hsiao

AbstractBreast cancer (BC) is the most common cancer and the leading cause of cancer-related deaths in women worldwide. The 5-year survival rate is over 90% in BC patients, but once BC cells metastasis into distal organs, it is dramatically decreasing to less than 30%. Especially, triple-negative breast cancer (TNBC) patients usually lead to poor prognosis and survival because of metastasis. Understanding the underline mechanisms of TNBC metastasis is a critical issue.