Yi-Chieh Yang

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Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma | Cell Death & Disease

1 month ago | nature.com | Wei-Jiunn Lee |Michael Hsiao |Shun-Fa Yang |Yi-Chieh Yang

AbstractThe intricate involvement of the histaminergic system, encompassing histamine and histamine receptors, in the progression of diverse neoplasias has attracted considerable scrutiny. Histamine receptor H1 (HRH1) was reported to be overexpressed in several cancer types, but its specific functional implications in oral squamous cell carcinoma (OSCC) predominantly remain unexplored.

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