Michael J. Tisza

Apr 5, 2024 | digitalcommons.library.tmc.edu | Justin Clark |Austen L. Terwilliger |Vasanthi Avadhanula |Michael J. Tisza

Home > UTHealth > UTHSPH > Journal Articles > 45 Journal Articles Frontiers in Public Health Humans, Wastewater, SARS-CoV-2, COVID-19, Pandemics, Public Health DOWNLOADS COinS...

Oct 28, 2023 | nature.com | Michael J. Tisza |Matthew Ross |David M. Henke |Blake Hansen |Kehe Zhang |Cici Bauer | +1 more

AbstractWastewater is a discarded human by-product, but its analysis may help us understand the health of populations. Epidemiologists first analyzed wastewater to track outbreaks of poliovirus decades ago, but so-called wastewater-based epidemiology was reinvigorated to monitor SARS-CoV-2 levels while bypassing the difficulties and pit falls of individual testing. Current approaches overlook the activity of most human viruses and preclude a deeper understanding of human virome community dynamics.

Sep 29, 2023 | biorxiv.org | Michael J. Tisza |Richard Lloyd |Kristi Hoffman |Daniel Smith

AbstractHumans are colonized with commensal bacteria soon after birth, and, while this colonization is affected by lifestyle and other factors, bacterial colonization proceeds through well-studied phases. However, less is known about phage communities in early human development due to small study sizes, inability to leverage large databases, and lack of appropriate bioinformatics tools.

Jul 10, 2023 | nature.com | Michael J. Tisza

Isolate storage, growth, and identificationHistorical BFG isolates originally cultured from clinical material between 1973 and 2018 were stored either lyophilized or frozen in skim milk media at the National Institutes of Health Clinical Center Department of Laboratory Medicine (Bethesda, MD). Isolates were de-identified and metadata including year and source/site of culture was maintained.