Michael Mints

May 31, 2023 | nature.com | Michael Tyler |Rouven Hoefflin |Roi Tschernichovsky |Thomas Barrett |Michael Mints |Avishay Spitzer | +2 more

AbstractEach tumour contains diverse cellular states that underlie intratumour heterogeneity (ITH), a central challenge of cancer therapeutics1. Dozens of recent studies have begun to describe ITH by single-cell RNA sequencing, but each study typically profiled only a small number of tumours and provided a narrow view of transcriptional ITH2.