Michael Roden

Jan 10, 2025 | nature.com | Christian Herder |Michael Roden

AbstractInflammation is a probable biological pathway underlying the relationship between diabetes and depression, but data on differences between diabetes types and symptom clusters of depression are scarce. Therefore, this cross-sectional study aimed to compare associations of a multimarker panel of biomarkers of inflammation with depressive symptoms and its symptom clusters between people with type 1 diabetes (T1D) and type 2 diabetes (T2D).

Mar 12, 2024 | nature.com | Christian Herder |Michael Roden

In a recent study published in Nature, Nobs and colleagues aimed to identify novel mechanisms that may explain why diabetes is associated with an increased susceptibility to viral respiratory infections.

Sep 7, 2023 | nature.com | Niclas Eriksson |Erin Macdonald-Dunlop |Stefan Enroth |Domenico Cozzetto |Lasse Folkersen |Christian Herder | +16 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01588-w, published online 10 August 2023. In the version of the article originally published, the middle panel in Fig. 3b was mistakenly a duplicate of the upper panel. The figure has now been corrected in the HTML and PDF versions of the article.

Aug 10, 2023 | nature.com | Niclas Eriksson |Erin Macdonald-Dunlop |Stefan Enroth |Domenico Cozzetto |Lasse Folkersen |Christian Herder | +16 more

AbstractCirculating proteins have important functions in inflammation and a broad range of diseases. To identify genetic influences on inflammation-related proteins, we conducted a genome-wide protein quantitative trait locus (pQTL) study of 91 plasma proteins measured using the Olink Target platform in 14,824 participants. We identified 180 pQTLs (59 cis, 121 trans).

Jun 16, 2023 | nature.com | Michael Roden

In a recent study published in Nature Medicine, Witkowski and colleagues applied untargeted metabolomics studies in 1157 people at high risk for cardiovascular disease, comprising 22% with diabetes mellitus, followed by quantitative targeted analyses to identify circulating metabolites associated with an increased cardiovascular risk.1 Their analyses revealed an association between plasma erythritol and major cardiovascular events—defined as the composite of death, myocardial infarction, and...