Michelle Henderson

Nov 5, 2024 | nature.com | Hansen Kosasih |Chelsea Mayoh |Michelle Henderson |Toby Trahair |Adam Patterson

AbstractT-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that expresses high levels of the enzyme aldo-keto reductase family 1 member C3 (AKR1C3). To exploit this finding, we developed a novel prodrug, ACHM-025, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent.

Mar 29, 2024 | thecourier.co.uk | Michelle Henderson

Stagecoach is in the running to be named the ‘best bus service’ in Scotland. The Perth-based bus and coach operator has been shortlisted in several categories in this year’s Scottish Transport Awards. It has received 10 nominations ranging from ‘best bus service’, ‘excellence in technology and innovation’ and top ‘public transport operator’. It comes as the firm is under fire for cuts to services across Perthshire.

Sep 20, 2023 | thelimbic.com | Michelle Henderson

Australia is entering what some are predicting to be a severe bushfire season. Are bushfires implicated in air pollution and can they have the same impact in driving cancer? The truth is, we don’t know how long you need to be exposed (to air pollution) for. Some of the exposures you get if you are close to a bushfire are very much higher to what you’d experience daily in a city with high levels of air pollution.