Mika Kivimäki

Aug 13, 2024 | nature.com | Michael Duggan |Pyry N Sipilä |Joni V Lindbohm |Yifei Lu |Christos Davatzikos |Guray Erus | +7 more

AbstractInfections have been associated with the incidence of Alzheimer disease and related dementias, but the mechanisms responsible for these associations remain unclear. Using a multicohort approach, we found that influenza, viral, respiratory, and skin and subcutaneous infections were associated with increased long-term dementia risk. These infections were also associated with region-specific brain volume loss, most commonly in the temporal lobe.

May 22, 2024 | nature.com | Mika Kivimäki |Keenan A. Walker

A study in Nature Aging on electronic health records from 1.7 million people in New Zealand reveals that most patients with dementia have a history of hospital-treated infection. In a dementia-free population, individuals with a severe infection were at a threefold-higher risk of dementia even 25 years later.

May 2, 2024 | thelancet.com | Mika Kivimäki |G David Batty

In the 2023 Lancet Series on work and health, the authors describe the risks to mental and physical health from stressful working conditions, such as job strain, workplace bullying, and long working hours. Putting this evidence into a wider context by examining the impact of a stressful work environment alongside lifestyle-related factors on ill-health is important. 1Effects of stress on the development and progression of cardiovascular disease.

Mar 13, 2024 | jnnp.bmj.com | Emma Anderson |Neil Davies |Roxanna Korologou-Linden |Mika Kivimäki

Dementia prevention: the Mendelian randomisation perspective Free Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Mar 7, 2024 | nature.com | Mika Kivimäki

Recent analyses of observational data from 340,000 UK Biobank participants indicate that people with a higher biological age than their same-aged peers have an increased risk of developing cardiometabolic diseases. By contrast, the ability of accelerated biological aging to predict multimorbidity progression is relatively limited.