Miklos Diossy

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"Frequent CHD1 Deletions in Prostate Cancers of African American Men Is" by Miklos Diossy, Viktoria Tisza et al.

Jan 6, 2025 | digitalcommons.library.tmc.edu | Miklos Diossy |Viktoria Tisza |Hua Li |Pranshu Sahgal

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Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression - npj Precision Oncology

Sep 18, 2024 | nature.com | Miklos Diossy |Pranshu Sahgal |Judit Börcsök |Dávid Szüts |Alan D. D’Andrea |István Csabai | +2 more

AbstractWe analyzed genomic data from the prostate cancer of African- and European American men to identify differences contributing to racial disparity of outcome. We also performed FISH-based studies of Chromodomain helicase DNA-binding protein 1 (CHD1) loss on prostate cancer tissue microarrays. We created CHD1-deficient prostate cancer cell lines for genomic, drug sensitivity and functional homologous recombination (HR) activity analysis.

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