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Articles

Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases

Sep 2, 2024 | cell.com | Charité Universitätsmedizin Berlin |Campus Lübeck |Cellular Bioengineering |Miltenyi Biotec B.V

KeywordsCD4 T cell exhaustionautoantigen-specific T cellsantigen-reactive T cell enrichment, ARTEautoimmune diseaseneuromyelitis opticaautoimmune hepatitisbullous pemphigoidMOGADCD154Foxp3IntroductionAutoimmune diseases (AIDs) result from the breakdown of self-tolerance mechanisms, leading to a chronic inflammatory autoimmune reaction and to tissue destruction.

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