Minneke J. Coenraad

Nov 27, 2023 | onlinelibrary.wiley.com | Nina Ajmone Marsan |J. Wouter Jukema |Minneke J. Coenraad |Roos A. Groen

Over 50%1 of patients with advanced liver cirrhosis present with cardiac dysfunction due to the dysregulation of the haemodynamic circulation, also known as cirrhotic cardiomyopathy (CCM). In particular, the vasodilatory effects secondary to portal hypertension cause hyperdynamic circulation, resulting in left ventricular (LV) systolic and/or diastolic dysfunction.

Jul 9, 2023 | onlinelibrary.wiley.com | Ruben Hernaez |Hai Li |Richard Moreau |Minneke J. Coenraad

The NACSELD Definition The North American Consortium for End-Stage Liver Disease (NACSELD) is a consortium of tertiary-care hepatology centres in the USA and Canada that prospectively collected data on hospitalized patients with cirrhosis admitted with or developed an infection during their hospitalization.44 Cirrhosis was defined by either (1) biopsy, (2) clinical evidence of decompensation or varices or (3) radiological evidence of liver nodularity and intra-abdominal varices in a patient...