Mirazul Islam

2 weeks ago | biorxiv.org | Mirazul Islam |Matthew Bechard |Yilin Yang |Alan Simmons

AbstractThe mammalian intestine regenerates rapidly after damage, yet the clonal dynamics and species-specific regulation of different populations remain poorly understood. Here we used synthetic or naturally occurring DNA alterations to reconstruct clonal histories of the mouse and human intestinal epithelium at single-cell resolution. In mice, we uncovered the clonal architecture of different cell types and their roles in regeneration, supporting a hierarchical regenerative response model.

Oct 30, 2024 | nature.com | Mirazul Islam |Yilin Yang |Alan Simmons |Naila Tasneem |Zhengyi Chen |Iannish D. Sadien | +9 more

AbstractTemporal ordering of cellular events offers fundamental insights into biological phenomena. Although this is traditionally achieved through continuous direct observations1,2, an alternative solution leverages irreversible genetic changes, such as naturally occurring mutations, to create indelible marks that enables retrospective temporal ordering3,4,5.

Sep 16, 2024 | preprints.org | Mirazul Islam

Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 13 September 2024 / Approved: 16 September 2024 / Online: 16 September 2024 (14:55:11 CEST) Islam, M. M. A Comprehensive Overview of The Principles, Design, Operation, And Optimization of a Three-Bed TSA Dryer for Hydrogen Gas Dehydration. Preprints 2024, 2024091255. https://doi.org/10.20944/preprints202409.1255.v1 Islam, M. M.