Mitchell Lee

Aug 7, 2024 | mdpi.com | Akshaya Lakshmi Thananjeyan |Jennifer Arnold |Mitchell Lee |Cheryl Au

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May 25, 2024 | biorxiv.org | Samantha McLean |Mitchell Lee |Weiqiang Liu |Rohil Tantray

AbstractCaloric restriction (CR) is known to extend lifespan across different species and holds great promise for preventing human age-onset pathologies. However, two major challenges exist. First, despite extensive research, the mechanisms of lifespan extension in response to CR remain elusive. Second, genetic differences causing variations in response to CR and genetic factors contributing to variability of CR response on lifespan are largely unknown.

Mar 17, 2024 | biorxiv.org | Samantha McLean |Mitchell Lee |Weiqiang Liu |Rohil Tantray

AbstractCaloric restriction (CR) is known to extend lifespan across different species and holds great promise for preventing human age-onset pathologies. However, two major challenges exist. First, despite extensive research, the mechanisms of lifespan extension in response to CR remain elusive. Second, genetic differences causing variations in response to CR and genetic factors contributing to variability of CR response on lifespan are largely unknown.