Mo Liu

Feb 14, 2024 | nature.com | Lei Chen |Chong Zhang |Ruidong Xue |Mo Liu |Yin Wang |Nanhai Jiang | +9 more

AbstractOver half of hepatocellular carcinoma (HCC) cases diagnosed worldwide are in China1,2,3. However, whole-genome analysis of hepatitis B virus (HBV)-associated HCC in Chinese individuals is limited4,5,6,7,8, with current analyses of HCC mainly from non-HBV-enriched populations9,10. Here we initiated the Chinese Liver Cancer Atlas (CLCA) project and performed deep whole-genome sequencing (average depth, 120×) of 494 HCC tumours.