Mrinal K. Sarkar

Dec 6, 2023 | frontiersin.org | Mrinal K. Sarkar |Olesya Plazyo |Shruthi Shanmukha

Highlights● DNA damage accumulation is increased in blood mononuclear cells of PsA patients● Levels of DNA damage correlate with CRP levels in PsA● Type-I Interferon pathway is paradoxically downregulated in PsAIntroductionPsoriatic arthritis (PsA) is a common inflammatory arthropathy, affecting about 25% of patients with psoriasis. It is heterogenous with many clinical manifestations, including arthritis, skin psoriasis, enthesitis, nail involvement and dactylitis.