Mugtaba Swar-Eldahab

Jul 6, 2024 | biorxiv.org | Holly Conway |dianna perez |Mugtaba Swar-Eldahab |Jon Pignanelli

AbstractType 1 diabetes (T1D) results in immune-mediated destruction of insulin-producing beta cells I the pancreas. B cells have been identified as critical antigen presenting cells and their specificity drives disease progression. More recently, they have also been shown to have the capacity to develop into suppressive, regulatory B cells that ameliorate autoimmune disease in animal models of rheumatoid arthritis and multiple sclerosis.