Muhammad Shahzeb

Jul 31, 2024 | bmcnephrol.biomedcentral.com | Muhammad Shahzeb

In the phase 3 FIDELIO-DKD and FIGARO-DKD clinical trials, patients with CKD associated with T2D received either finerenone or placebo on a background of the maximum tolerated dose of a RAAS inhibitor [12, 13, 66]. Other baseline medications in FIDELIO-DKD included an SGLT2i in 4.6% of patients and a GLP-1 RA in 6.9% of patients, while in FIGARO-DKD, 8.4% of patients received an SGLT2i and 7.5% received a GLP-1 RA [12, 13].

Jul 16, 2024 | academic.oup.com | Humboldt-Universität zu Berlin |Muhammad Shahzeb |Universitätsmedizin Berlin

Cardiac wasting (i.e. the loss of heart muscle) has been observed in late stages of several chronic diseases that are linked to whole body cachexia—including heart failure.1 Likewise, this has also been seen in severely malnourished patients with anorexia nervosa.2 Studies that assessed cardiac wasting in preclinical models found that the main mechanisms responsible for cardiac wasting include disrupted cardiomyocyte ultrastructure, fibrosis, and proteolysis.3 Cardiac wasting can occur due to...

Aug 26, 2023 | academic.oup.com | Baylor Scott |Muhammad Shahzeb |van Veldhuisen |CSL Vifor

See the editorial comment for this article ‘Intravenous iron repletion in heart failure: bridging the gap between symptom relief and hard clinical outcomes’, by H. Abu-Own et al., https://doi.org/10.1093/eurheartj/ehad746.

Aug 12, 2023 | academic.oup.com | Muhammad Shahzeb |Baylor Scott

Research has transformed the practice of medicine from primarily an anecdote and experience-based discipline to an evidence-based profession, both in terms of benefit and also risks. These evidences then form the basis of practice guidelines that are widely used by clinicians, policymakers, funders of research, payers, and patients alike. The impact of medical research in saving and improving lives is indisputable.

Jun 9, 2023 | docker.com | Muhammad Shahzeb |Ajeet Raina

More than one million, that’s the number of active Grafana installations worldwide. In the realm of data visualization and monitoring, Grafana has emerged as a go-to solution for organizations and individuals alike. With its powerful features and intuitive interface, Grafana enables users to gain valuable insights from their data.