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Jan 22, 2025 | 
medicalxpress.com | Nagoya City
A research group from Nagoya City University has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).The findings of the study are published in Science Advances. Birth is one of the most significant life events for animals. The transition from the intrauterine to the extrauterine environment causes various metabolic changes in individuals. Despite its significance, the role of birth in the developmental process remains incompletely understood.
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Dec 30, 2024 | 
scitechdaily.com | Nagoya City
M87, a prominent galaxy in the Virgo cluster, gained fame after the Event Horizon Telescope (EHT) revealed the first image of a black hole in its center. A subsequent study analyzed data from EHT’s 2018 campaign, reporting a rare gamma-ray flare — marking the first in over a decade — linked to the galaxy’s supermassive black hole.
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Dec 1, 2024 | 
bmcnephrol.biomedcentral.com | Nagoya City
We conducted a non-interventional, population-based cohort study using the Japanese Medical Claims Database acquired from Medical Data Vision Co., Ltd. Data were obtained from 36,690,000 patients in 449 hospitals between April 2008 and August 2021. The database included individual records of prescriptions, procedures, surgeries, hospitalisations, and laboratory data.
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Nov 27, 2024 | 
phys.org | Nagoya City
A collaborative research group, including researchers from Nagoya City University, National Institutes of Natural Sciences, and RIKEN has uncovered a molecular tool, the "passport sequence," that significantly improves the production efficiency and quality of glycoproteins, such as blood coagulation factor VIII and erythropoietin (EPO).
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Sep 29, 2024 | 03174-2/fulltext?rss=yes&sz=64)
redjournal.org | Outcomes Research |Nagoya City |Imaging Clinic
IntroductionLung cancer has been the leading cause of death among all types of cancers since 1998, with 126,548 people having received diagnoses of lung cancer in 2019 in Japan.11. Center for Cancer Control and Information Services, The number of lung cancer patients. National Cancer Center, Japan. Accessed May 10, 2024. https://ganjoho.jp/reg_stat/statistics/stat/cancer/12_lung.html Non-small cell lung cancer (NSCLC) accounts for 90% of all the whole lung cancer cases in Japan.22.
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Sep 29, 2024 | 03174-2/fulltext&sz=64)
redjournal.org | Ataru Igarashi |Outcomes Research |Nagoya City |Imaging Clinic
Introduction Lung cancer has been the leading cause of death among all types of cancers since 1998, with 126,548 people having received diagnoses of lung cancer in 2019 in Japan.1 Non-small cell lung cancer (NSCLC) accounts for 90% of all the whole lung cancer cases in Japan.2 According to recent clinical practice guidelines published by the Japan Lung Cancer Society in 2023, surgery is recommended as the first choice for medically operable patients with stage I NSCLC,3 with stereotactic body...
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Jun 21, 2024 | 
link.springer.com | Nagoya City
AbstractGood accuracy for the clinical diagnosis of frontotemporal lobar degeneration (FTLD) by specialists in an early onset dementia clinic has been reported. To assess the diagnostic accuracy of FTLD in an entire population, without restrictions related to patient age or diagnosing physician. Volumes of the “Annual of the Pathological Autopsy Cases in Japan,” with reports of 130,105 autopsies throughout Japan from 2007 to 2016, were descriptively analyzed.
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Mar 11, 2024 | 
medicalxpress.com | Nagoya City
The structure and functions of the tip of migrating neurons remain elusive. A research group has found that the PTPÏ-expressing growth cone senses the extracellular matrix and drives neuronal migration in the injured brain, leading to functional recovery. The full findings of the study are published in a paper titled, "Identification of the growth cone as a probe and driver of neuronal migration in the injured brain," in Nature Communications.
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Mar 6, 2024 | 
academic.oup.com | Kyoto Prefectural |Nagoya City
Objectives: To update an evidence base informing the 2024 JCR clinical practice guidelines (CPGs) for the management of rheumatoid arthritis (RA) in older adults. Methods: Four clinical questions (CQs) regarding efficacy and safety of drug treatment were evaluated, with CQ1 addressing methotrexate (MTX), CQ2 biological disease-modifying antirheumatic drugs (bDMARDs), CQ3 Janus kinase (JAK) inhibitors, and CQ4 glucocorticoids (GCs).
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Dec 22, 2023 | 
link.springer.com | Nagoya City
AbstractTo develop a machine learning (ML)-based model for predicting the addition of clinically significant adverse reaction (CSAR)-associated information to drug package inserts (PIs) based on information of adverse drug reaction (ADR) cases during the post-marketing stage in Japan. We collected data on CSARs added to PIs from August 2011 to March 2020.
