Natalie A. Hamada

Jul 30, 2024 | nph.onlinelibrary.wiley.com | Fuai Sun |Natalie A. Hamada |Christian Montès |Yuanyuan Li

Introduction The SKP1-Cullin-F-box (SCF) complex is one of the best-studied E3 ubiquitin ligases in plants because of its critical roles in various signaling pathways (Lechner et al., 2006; Sadanandom et al., 2012; Stefanowicz et al., 2015; Abd-Hamid et al., 2020). The core components of SCF include Cullin 1 (CUL1) scaffold protein that interacts with SKP1 adaptor protein at the N-terminal, and E2-interacting RING-finger protein RBX1 at the C-terminal (Fig. 1a).