Natalie Put

Oct 15, 2024 | onlinelibrary.wiley.com | Sandrine Jayne |Cristina Lopez |Cristina Conde López |Christian-Albrechts-University Kiel |Natalie Put

INTRODUCTION Unlike other lymphoid malignancies, balanced, reciprocal chromosomal translocations are rare in chronic lymphocytic leukaemia (CLL).1 However, chromosomal translocation t(1;6)(p35.3;p25.2) has been previously described as a rare but recurrent event.2-5 The presence of this translocation in 12 previously reported cases of CLL has been associated with high-risk chromosomal aberrations like del(11q) and del(17p), unmutated IGHV status and a progressive clinical course (for review,...