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6 days ago | 
rheumatologyadvisor.com | natasha persaud
Immunological tests can differentiate proliferative from non-proliferative lupus nephritis, but anti-C1q antibodies and urinary erythrocytes have the best predictive power to distinguish disease class and identify kidney flare risk, investigators report. In a study, 61 patients underwent immunological tests and kidney biopsy on the same day.
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6 days ago | 
renalandurologynews.com | natasha persaud
Sodium glucose cotransporter 2 inhibitor (SGLT2i) use is associated with lower hyperkalemia risk among real-world patients taking renin angiotensin aldosterone system inhibitors (RAASi) to treat hypertension accompanying diabetes, chronic kidney disease (CKD), or heart failure.
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6 days ago | 
thecardiologyadvisor.com | natasha persaud
Proteinuria is associated with higher risk of sudden cardiac arrest in adults younger than 40 years, a Korean study finds. Pre‐existing chronic kidney disease (CKD) showed a particularly strong association. Investigators analyzed urine dipstick results from 6,891,400 South Korean adults aged 20 to 39 years undergoing health screening through the 2009-2012 national health insurance service. They identified proteinuria in 5362 individuals (0.08%).
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1 week ago | 
renalandurologynews.com | natasha persaud
Extrarenal lupus flares continue to occur in more than one-third of patients with end-stage kidney disease (ESKD) receiving renal replacement therapy (RRT), investigators report. Flare risk is higher for patients receiving dialysis vs a kidney transplant. Investigators performed a systematic review and meta-analysis of data from 29 observational studies published 1973-2023.
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1 week ago | 
renalandurologynews.com | natasha persaud
Immunological tests can differentiate proliferative from non-proliferative lupus nephritis, but anti-C1q antibodies and urinary erythrocytes have the best predictive power to distinguish disease class and identify kidney flare risk, investigators report. In a study, 61 patients underwent immunological tests and kidney biopsy on the same day.
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2 weeks ago | 
hematologyadvisor.com | natasha persaud
Having a low hemoglobin level or a high erythropoiesis-stimulating agent (ESA) resistance index (ERI) is associated with faster decline in residual kidney function in patients undergoing peritoneal dialysis, investigators report. Over 2.5 years, 659 of 1640 patients (40.2%) receiving peritoneal dialysis in the Japanese Society for Dialysis Therapy renal data registry experienced anuria. Urine volume decreased faster in those with anemia.
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2 weeks ago | 
oncologynurseadvisor.com | natasha persaud
Secondary rectal cancer after prostate cancer radiation therapy appears to have distinct clinical genomic characteristics and worse survival odds than primary rectal cancer, investigators report. In a case-control study, investigators compared outcomes from 64 men with secondary rectal cancer and 604 male patients with primary rectal cancer treated from 1994 to 2022.
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2 weeks ago | 
renalandurologynews.com | natasha persaud
Infusing prophylactic magnesium before initiating intravenous cisplatin for cancer treatment may lower the risk for cisplatin-induced acute kidney injury (CP-AKI), investigators suggest. CP-AKI is a frequent and serious complication of cisplatin treatment for many malignancies, such as advanced bladder cancer.
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3 weeks ago | 
thecardiologyadvisor.com | natasha persaud
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) may better protect against kidney and ureteral stones whether or not a patient has stone history, investigators suggest. Using the 2010-2021 Korea National Health Insurance Service database, investigators propensity-score matched 17,006 pairs of patients with type 2 diabetes newly treated with SGLT2is or dipeptidyl peptidase 4 inhibitors (DPP4is).
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1 month ago | 
renalandurologynews.com | natasha persaud
Children infected with SARS-CoV-2 who develop COVID-19 are more likely to experience new onset chronic kidney disease (CKD) and progressive CKD compared with uninfected children, according to findings from a large study. Among 1,900,146 pediatric patients younger than 21 years from 19 medical facilities in the 2020-2023 US National Institutes of Health Researching COVID to Enhance Recovery (RECOVER) initiative, 487,378 children (25.6%) experienced COVID-19.
