Nicholas L. Mills

Jul 8, 2024 | nature.com | Emma Copland |Defne Saatci |Nicholas L. Mills |Paul Moss |Aziz Sheikh |Chris Robertson

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-47745-z, published online 27 May 2024The original version of this article contained information on vaccine dose amount (full or half) in Table 2 and Supplementary Table 1. This has subsequently been found to be inaccurate due to inconsistent coding in the raw data. The vaccine dose amount has therefore been removed from Table 2 and Supplementary Table 1. This data was not used elsewhere in the analysis.

May 27, 2024 | nature.com | Emma Copland |Defne Saatci |Nicholas L. Mills |Paul Moss |Aziz Sheikh |Chris Robertson

AbstractThe risk-benefit profile of COVID-19 vaccination in children remains uncertain. A self-controlled case-series study was conducted using linked data of 5.1 million children in England to compare risks of hospitalisation from vaccine safety outcomes after COVID-19 vaccination and infection. In 5-11-year-olds, we found no increased risks of adverse events 1–42 days following vaccination with BNT162b2, mRNA-1273 or ChAdOX1.

May 13, 2024 | onlinecjc.ca | Peter Kavsak |Nicholas L. Mills |Dennis T. Ko |Steven Friedman

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Mar 20, 2024 | jamanetwork.com | Nicholas L. Mills

Type 2 myocardial infarction (T2MI) is caused by ischemia from reduced oxygen supply, increased demand, or both, without acute atherothrombosis. Multiple nonatherosclerotic factors can reduce myocardial oxygen supply, including coronary pathology such as vasospasm, dissection, or embolism, as well as noncoronary processes such as anemia, hypoxemia, and hypotension. Similarly, multiple factors increase oxygen demand including severe hypertension, tachycardia, and fever.

Feb 11, 2024 | nature.com | Nicholas L. Mills

In coronary artery disease, the transition from an apparently stable state to a life-threatening acute cardiac event is difficult to predict. As such, a recent study applied proteomic and metabolomic approaches to discover new biomarkers that signal imminent myocardial infarction.