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Aug 13, 2024 | 
nature.com | Stuart Bedston |Gavin M Jamie |Chris Robertson |Ashley Akbari |Aziz Sheikh |Xinchun Gu
AbstractVaccines against COVID-19 and influenza can reduce the adverse outcomes caused by infections during pregnancy, but vaccine uptake among pregnant women has been suboptimal. We examined the COVID-19 and influenza vaccine uptake and disparities in pregnant women during the COVID-19 pandemic to inform vaccination interventions.
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Jul 8, 2024 | 
nature.com | Emma Copland |Defne Saatci |Nicholas L. Mills |Paul Moss |Aziz Sheikh |Chris Robertson
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-47745-z, published online 27 May 2024The original version of this article contained information on vaccine dose amount (full or half) in Table 2 and Supplementary Table 1. This has subsequently been found to be inaccurate due to inconsistent coding in the raw data. The vaccine dose amount has therefore been removed from Table 2 and Supplementary Table 1. This data was not used elsewhere in the analysis.
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Jun 13, 2024 | 
nature.com | Calum Macdonald |Norah E Palmateer |Laura Lindsay |Safraj Shahul Hameed |Karen Jeffrey |Luke Daines | +9 more
AbstractSeveral population-level studies have described individual clinical risk factors associated with suboptimal antibody responses following COVID-19 vaccination, but none have examined multimorbidity. Others have shown that suboptimal post-vaccination responses offer reduced protection to subsequent SARS-CoV-2 infection; however, the level of protection from COVID-19 hospitalisation/death remains unconfirmed.
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Jun 13, 2024 | nature.com | Calum Macdonald |Norah E Palmateer |Laura Lindsay |Safraj Shahul Hameed |Karen Jeffrey |Luke Daines | +9 more
AbstractSeveral population-level studies have described individual clinical risk factors associated with suboptimal antibody responses following COVID-19 vaccination, but none have examined multimorbidity. Others have shown that suboptimal post-vaccination responses offer reduced protection to subsequent SARS-CoV-2 infection; however, the level of protection from COVID-19 hospitalisation/death remains unconfirmed.
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May 27, 2024 | 
nature.com | Emma Copland |Defne Saatci |Nicholas L. Mills |Paul Moss |Aziz Sheikh |Chris Robertson
AbstractThe risk-benefit profile of COVID-19 vaccination in children remains uncertain. A self-controlled case-series study was conducted using linked data of 5.1 million children in England to compare risks of hospitalisation from vaccine safety outcomes after COVID-19 vaccination and infection. In 5-11-year-olds, we found no increased risks of adverse events 1–42 days following vaccination with BNT162b2, mRNA-1273 or ChAdOX1.
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Jan 16, 2024 | 
nature.com | Chris Robertson |Declan T. Bradley |Ting Shi |Simon de Lusignan |Aziz Sheikh
AbstractThe emergence of the COVID-19 vaccination has been critical in changing the course of the COVID-19 pandemic. To ensure protection remains high in vulnerable groups booster vaccinations in the UK have been targeted based on age and clinical vulnerabilities. We undertook a national retrospective cohort study using data from the 2021 Census linked to electronic health records.
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Oct 12, 2023 | 00626-6/abstract&sz=64)
thelancet.com | Colin Simpson |Chris Robertson |Jim McMenamin
The Scottish Early Estimation of Pandemic Influenza Antiviral and Vaccine Effectiveness (EAVE) platform was established in 2012 through funding from the National Institute for Health Research, alongside a portfolio of nine pandemic preparedness and responsiveness projects consequent to the 2009 influenza A/H1N1 pandemic.In response to the emergence of COVID-19, funding was made available by a range of UK funders to support studies that could rapidly respond to this new pandemic.
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Aug 29, 2023 | 
nature.com | Laura Lindsay |Clara Calvert |Ting Shi |Cheryl A Denny |Leanne Hopkins |Anna Goulding | +8 more
AbstractUnderstanding the impact of SARS-CoV-2 infection and COVID-19 vaccination in pregnancy on neonatal and maternal outcomes informs clinical decision-making. Here we report a national, population-based, matched cohort study to investigate associations between SARS-CoV-2 infection and, separately, COVID-19 vaccination just before or during pregnancy and the risk of adverse neonatal and maternal outcomes among women in Scotland with a singleton pregnancy ending at ≥20 weeks gestation.
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May 19, 2023 | 
voegelinview.com | Chris Robertson
Having mighty but humble heroes has long been a part of Western culture, but they weren’t always the way they are seen now. For years, long before the Christianization of places like England, heroes were more prideful. It wasn’t until the Christians of the early Middle Ages migrated to the British Isles that the great heroes of English literature started to form into the humble souls as now seen. Humility is a Christian virtue because it is believed that God also plays a part in one’s success.
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Apr 27, 2023 | 00444-0/abstract&sz=64)
thelancet.com | Utkarsh Agrawal |Chris Robertson |Aziz Sheikh
We welcome the Correspondence from Westyn Branch-Elliman and Paul A Monach in which they hypothesise that there are some individuals who, after completion of their primary COVID-19 vaccination course, do not need frequent vaccine re-dosing; others who might benefit from periodic re-dosing; and others who could, irrespective of the number of doses given, respond poorly to vaccines. 1Factors associated with severe COVID-19 among vaccinated adults treated in US Veterans Affairs hospitals.
