Nicola Vickaryous

Jan 28, 2024 | onlinelibrary.wiley.com | Benjamin Jacobs |Nicola Vickaryous |Gavin Giovannoni |Petroula Proitsi

Introduction Blood-based protein biomarkers have several properties which make them attractive adjuncts in the diagnosis, monitoring, and prognostication of multiple sclerosis (MS). Proteins are often abundant in serum/plasma, stable in solution, and are straightforward to quantify. Furthermore plasma is easier to obtain than cerebrospinal fluid or magnetic resonance imaging (MRI) scans, particularly if regular measurements are required for ongoing monitoring.

Nov 20, 2023 | medrxiv.org | Benjamin Jacobs |Nicola Vickaryous |Gavin Giovannoni |Petroula Proitsi

The authors have declared no competing interest. BMJ is funded by a Medical Research Council (MRC) Clinical Research Training Fellowship (CRTF) jointly supported by the UK MS Society (BMJ; grant reference MR/V028766/1), and by Barts Charity. The Preventive Neurology Unit is supported by a grant from Barts Charity. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.