Nicole Weckman

Sep 23, 2024 | biorxiv.org | Chalmers C Chau |Nicole Weckman |Emma Thomson |Paolo Actis

AbstractThe field of nanopore sensing is now moving beyond nucleic acid sequencing. An exciting new avenue is the use of nanopore platforms for the monitoring of biochemical reactions. Biological nanopores have been used to investigate the dynamics of enzymatic reactions but solid-state nanopore approaches have lagged. This is partially due to the necessity of using higher salt conditions (e.g. 4M LiCl) to improve the signal-to-noise ratio.

Sep 4, 2023 | nature.com | Sarah Sandler |Nicole Weckman |Sarah Yorke |Kaikai Chen

Correction to: Nature Biomedical Engineering https://doi.org/10.1038/s41551-023-01078-2. Published online 7 August 2023. In the version of this article initially published, the surname of Richard Gutierrez appeared as “Guitterez”. The spelling has been corrected in the HTML and PDF versions of the article.

Aug 7, 2023 | nature.com | Sarah Sandler |Nicole Weckman |Sarah Yorke |Kaikai Chen

AbstractSingle-molecule quantification of the strength and sequence specificity of interactions between proteins and nucleic acids would facilitate the probing of protein–DNA binding.