Paolo Actis

Sep 23, 2024 | biorxiv.org | Chalmers C Chau |Nicole Weckman |Emma Thomson |Paolo Actis

AbstractThe field of nanopore sensing is now moving beyond nucleic acid sequencing. An exciting new avenue is the use of nanopore platforms for the monitoring of biochemical reactions. Biological nanopores have been used to investigate the dynamics of enzymatic reactions but solid-state nanopore approaches have lagged. This is partially due to the necessity of using higher salt conditions (e.g. 4M LiCl) to improve the signal-to-noise ratio.