Nicoletta Marchesi

Dec 4, 2024 | mdpi.com | Nicoletta Marchesi |Alessia Pascale |Annalisa Barbieri |Martina Capierri

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Aug 10, 2023 | frontiersin.org | Pedro Ramos-Cabrer |Jun-Jie Zhang |Nicoletta Marchesi

1. Introduction Acute ischemic stroke (AIS), one of the leading causes of disability and death worldwide (1, 2), is characterized by high incidence, high recurrence, and high mortality. Hypertension is regarded as a primary risk factor for AIS (1, 3), and most hypertensive patients are accompanied by an increase in serum homocysteine (Hcy) (4, 5), which is defined as H-type hypertension (HHTN), which means a combination of essential hypertension and a high level of Hcy (6).