Nikolaos Kanellakis

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Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity - Nature Immunology

Apr 1, 2024 | nature.com | Pablo F. Céspedes |Uzi Gileadi |Zhu Liang |Fei Gao |Nikolaos Kanellakis |Yi-Ling Chen | +7 more

AbstractCancer remains one of the leading causes of mortality worldwide, leading to increased interest in utilizing immunotherapy strategies for better cancer treatments. In the past decade, CD103+ T cells have been associated with better clinical prognosis in patients with cancer. However, the specific immune mechanisms contributing toward CD103-mediated protective immunity remain unclear.

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