Noah Reis

Apr 24, 2024 | nature.com | Xiaoyu Chen |Fikri Birey |Min-Yin Li |Noah Reis |Jin Hao |Xiangling Meng

AbstractTimothy syndrome (TS) is a severe, multisystem disorder characterized by autism, epilepsy, long-QT syndrome and other neuropsychiatric conditions1. TS type 1 (TS1) is caused by a gain-of-function variant in the alternatively spliced and developmentally enriched CACNA1C exon 8A, as opposed to its counterpart exon 8.

Sep 27, 2023 | nature.com | Xiangling Meng |Kent Imaizumi |Noah Reis |Michael Bassik

AbstractThe assembly of cortical circuits involves the generation and migration of interneurons from the ventral to the dorsal forebrain1,2,3, which has been challenging to study at inaccessible stages of late gestation and early postnatal human development4.